DSEK

Descemet’s Stripping Endothelial Keratoplasty

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In Numbers

3000+ Total Cornea surgeries performed till time at LJ Eye Institute.

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Demographics

Patients from Haryana, Punjab, Himachal Pradesh, J&K, & Rajasthan, trusts LJEI.

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Technology / Innovation

LJEI is equipped with all the latest and rare Machines / Technology including AI.

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Research

We preserve every single case study to handle any complex situation and publish research papers time to time.

DMEK Surgery in Haryana | Cornea Surgeries in India

DSEK Surgery In India

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What is DSEK surgery and who need it?

Descemet’s Stripping Endothelial Keratoplasty (DSEK) is a procedure that involves replacing only the innermost layer of the cornea, rather than the entire thickness of the cornea, as is performed in standard full-thickness corneal transplantation. For patients who have conditions such as Fuchs corneal dystrophy or swelling of the cornea after cataract surgery, corneal clouding is caused by dysfunction of the cells that make up the innermost layer of the cornea, called the corneal endothelium. The corneal endothelial cells function to pump fluid out of the cornea. When these cells are damaged or reduced in number, the cornea swells, resulting in corneal clouding and loss of vision. Even though the other layers of the cornea are healthy, this condition has traditionally been treated with full-thickness corneal transplantation to bring a new layer of endothelial cells to the patient’s eye.

DSEK surgery involves peeling only the diseased endothelial layer from the back of the patient’s cornea, leaving the remaining 95% of the cornea, which is healthy, untouched. The posterior layer of a healthy donor cornea is then placed inside the eye through a small incision and positioned with an air bubble to replace the diseased layer that was removed. DSEK is performed in less than one hour without any sutures in the cornea.

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Cornea Helpline

Why To Choose LJ Eye Institute for DSEK Surgery?

We have the most experienced surgeon in the region, Ddr. Vikas Mittal who performed more than 1000 DALK Surgery. Our graft rejection rate is less than 5%.

DALK can be performed in Corneal ectatic disorders like Keratoconus, Post LASIK Ectasia, Pellucid marginal corneal degeneration (PMCD). The bulged out cornea (forward bending making it a conical shape) in these disorders makes the focus in patient eye distorted and blurry. In this surgery, only front layers of cornea (stroma) is first cut with advanced corneal trephines and later dissected using special techniques and instruments. After this, same layers from a donated cornea is procured and then transplanted over patient’s eye. The ectatic or bulged out cornea is hence replaced by healthy cornea with appropriate shape. Use of Femtosecond laser in this surgery helps in avoiding use of trephine and various blades making it very accurate with diameter and depth of corneal layer transplantation. There is almost negligible risk of graft rejection and failure in this technique of cornea transplantation (Keratoplasty).

What to expect after DSEK surgery?

Your eye will take 6-8 weeks to heal. It is normal for your eye to be red, slightly uncomfortable, light sensitive, teary and blurred immediately following surgery. These symptoms will gradually improve within the first 3 weeks.

What are the restrictions after a partial corneal transplant?

Do not wear eye makeup until your doctor says it’s okay. You may also want to avoid face cream or lotion. Avoid heavy lifting for about 4 weeks, or until your doctor says it is okay. Avoid swimming, hot tubs, gardening, and dusting for 2 to 4 weeks.

How long does DSEK last?

A DSEK procedure is done with the patient under local anesthesia. The procedure takes just 45 minutes, about half the time needed for a traditional cornea transplant.

How successful is DSEK surgery?

At 10 years, DSEK survival rate was 79% for all eyes, including complex grafts, and ECL was 73%.

Can I watch TV after a cornea transplant?

Refrain from any eye makeup for 7 days following surgery. Avoid strenuous activity. You may read and watch TV as much as you would like. You may resume work and driving when you feel ready.

What is the recovery time for cornea surgery?

during the first weeks after surgery, avoid strenuous exercise and heavy lifting. if you have a job that does not involve physical strain, you can return to work 2 to 3 weeks after surgery. if your job involves manual labour, you should wait for 3 to 4 months.

What is the vision after DSEK?

By three months, the vision is usually around 20/50 or better, but this is highly variable, with many patients achieving 20/30 or so. At one year after surgery, over 65% of patients have 20/40 or better vision.

What causes failure of DSAEK?

The principal cause of failed DSAEK is endothelial cell loss. Residual host Descemet membrane, fibrocellular tissue at the edge of the lenticule, and epithelial implantation are common histologic findings. Fungal infection may occur in the setting of DSAEK.

Which is better DSEK or DMEK?

In clinical trials, DMEK has been shown to offer patients a slightly better quality of vision and to resume their daily activities quickly. There is also a slightly lower long-term risk of graft rejection with DMEK compared to DSEK.

What is the rejection rate of DSEK?

the average incidence of primary graft failure in Descemet stripping endothelial keratoplasty (DSEK) is 5%, and the incidence of mean endothelial rejection rate is 10%.

Can you have 20/20 vision after a cornea transplant?

A vision of 20/20 is possible, but even with a crystal-clear cornea, vision depends upon the function of the retina and may not attain 20/20. It is most important to remember that while the vision will be better than it was before surgery, vision improvement varies among all patients.

Can I travel after corneal transplant?

Following DMEK and DSAEK, patients may not fly or drive to an elevation greater than 2,000 ft to avoid elevated pressure caused by the bubble used to attach the transplant tissue. The bubble is generally only big enough to limit travel for 1 day following DSAEK and for 4-5 days following DMEK.

Can cornea be replaced twice?

Corneal transplants can be re-transplanted if they fail, scar, or produce poor vision. Transplants can be repeated multiple times as long as there is a reasonable chance of success and the eye and patient can tolerate additional procedures.

DSEK Surgeons at LJEI

Dr. Vikas Mittal

Performed 2500+ DMEK Surgeries
20+ Years Experience

Dr. Neha Jain

Performed 800+ DMEK Surgeries
10+ Years Experience

What conditions can be treated with DSEK?

DSEK is intended to transplant a healthy endothelial cell layer that will pump the fluid out of the cornea. It’s expected to restore corneal clarity and improve vision. This procedure corrects corneal endothelium failure, but is not able to correct corneal scarring, thinning or surface irregularity.

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Fuchs’ endothelial dystrophy

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Pseudophakic bullous keratopathy

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corneal decompensation following cataract surgery

Available Cornea Treatments at LJEI

DMEK Surgeries

DSEK Surgeries

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We feel proud to say that our doctors train various Cornea techniques to National and International doctors.

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Benefits of DSEK

Descemet’s Stripping Endothelial Keratoplasty represents a significant leap forward in the field of corneal transplantation, offering patients a safer, more effective alternative to traditional methods. With its ability to restore vision swiftly and reliably while minimising risks and complications, DSEK has revolutionised the way we approach corneal endothelial disorders. As technology and techniques continue to evolve, DSEK stands as a beacon of hope for those in need of vision restoration, paving the way for a brighter future in ophthalmic care.

The advantages of DSEK are manifold, making it a preferred choice for many patients and surgeons alike:

Rapid Visual Rehabilitation, Reduced Risk of Rejection, Enhanced Refractive Outcomes, Greater Surgical Precision, Shorter Recovery Time.

in DMEK doctors change innermost corneal layer

Technology @ LJEI

Technology Available For Cornea Treatments at LJEI

LJ Eye Institute employs ultra-advanced technologies for Cornea Transplant procedures.

We utilize Femtosecond LASER technology for Cornea Transplants, ensuring precision and accuracy compared to conventional blade methods.
Our facility is equipped with specialized equipment including Specular Microscope for assessing corneal power, Topography, Pentacam, Anterion, and OCT for comprehensive evaluation.
We integrate the latest available technologies from around the world to achieve the highest success rates in Cornea Transplants.
For pediatric cases, we have a dedicated spare system and have extensively researched Pediatric Cornea diseases, with publications in national and international medical journals.
LJ Eye Institute is at the forefront of Stem Cell Transplantation, particularly in the pioneering SLET technique, with numerous published papers showcasing our advancements and modifications in the field.