Complex Cornea Problems Treatment Centre & Research Institute
LJ Eye Institute - Ambala
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Corneal Collagen Cross Linking

Corneal cross-linking is a treatment for an eye problem called Keratoconus.

In Numbers

5000+ Total Keratoconus surgeries performed till time at LJ Eye Institute.

Demographics

Patients from Haryana, Punjab, Himachal Pradesh, J&K, & Rajasthan, trusts LJEI.

Technology / Innovation

LJEI is equipped with all the latest and rare Machines / Technology including AI.

Research

We preserve every single case study to handle any complex situation and publish research papers time to time.

CXL Corneal Collagen Cross Linking at LJ Eye Institute

CXL

What is Corneal Collagen Cross Linking?

Corneal cross-linking is a treatment for an eye problem called Keratoconus.

In this condition, the front part of your eye, called the cornea, thins out and gets weaker over time. This makes it bulge into a cone shape, which can distort your vision and make it hard to see. If the symptoms of keratoconus get severe, you will need a corneal transplant.

In corneal cross-linking, doctors use eyedrop medication and ultraviolet (UV) light from a special machine to make the tissues in your cornea stronger. The goal is to keep the cornea from bulging more.

It’s called “cross-linking” because it adds bonds between the collagen fibers in your eye. They work like support beams to help the cornea stay stable.

Corneal cross-linking is the only treatment that can stop progressive Keratoconus from getting worse. And it may help you avoid a corneal transplant, which is major surgery.

Symptoms/Conditions

A healthy cornea resembles a clear, round dome. Located at the front of your eye, your cornea is what helps you to see, by focusing the light that enters through your eye.

In people with keratoconus, however, the cornea doesn’t have enough collagen fiber cross-links, which serve as a kind of structural support. Without those cross-links, the cornea begins to bulge out in a cone-like shape. That bulge results in blurred, distorted vision as the cornea weakens and thins. The condition, which can significantly impair vision, is difficult to treat with glasses. Severe cases of keratoconus may even require corneal transplant.

Symptoms of Keratoconus typically include blurred or distorted vision and increased sensitivity to light

What are the restrictions for collagen cross-linking?
Concentrated visual acuity decreases blinking and causes your eyes to become dry and vision to become unstable. Showers and baths are fine, but try to keep your eyes gently closed and avoid getting water and soap directly in your eyes for 5 days.
How long does collagen cross-linking last?
In simple terms, the younger the patient is at the first cross-linking, the higher the likelihood that they will need a second treatment after 7−8 years. The cornea is completely rebuilt every 7−8 years – a fact that has only recently come to light.
What can you not do after corneal cross-linking?
Showers are permitted, but try to avoid getting water directly in your eye for 2 weeks. Stay in a clean environment. Avoid gardening, swimming, hot tubs, and saunas for 4 weeks. Exercising is fine after the bandage contact is removed, DO NOT rub the sweat out of your eyes.
What vitamin is used for collagen cross-linking?
Vitamin B (riboflavin) eye drop medicine is applied to the cornea for about 30 minutes. Next, a special device shines a focused beam of UV light rays at your cornea for close to 30 minutes. The light activates the riboflavin in the cornea. This helps form new bonds between the collagen fibers in your cornea.
How successful is corneal collagen cross linking?
The corneal cross-linking success rate is 95%. For the 5% of patients who don’t respond to treatment, this is usually due to underlying health conditions disrupting the recovery process.
What is the purpose of collagen cross linking?
CXL is a technique of strengthening the corneal tissue by using riboflavin and ultraviolet-A light to halt the progression of progressive keratoconus. In CXL, riboflavin act as a photosensitizing agent, and UVA improves the formation of intra and interfibrillar covalent bonds by oxidative photosensitization.
Does collagen cross linking decrease with age?
The numbers of cross‐links within collagen molecules accumulate with age; as a result collagen molecules gradually lose mobility and become less soluble. The rigidity of collagen can also affect the ability of cells to transport nutrients and oxygen to cells and wastes away from cells.
What is the best age for corneal cross-linking?
The FDA approval age is 14; however, the earlier the disease is treated, the better. We know that cross-linking is effective and that preventing the development of visually devastating keratoconus is a significant quality of life enhancer.
Can I watch TV after crosslinking?

After procedure no reading, computer use, or television for remainder of this day and night. You may open your eye to use the bathroom, to walk, and to eat. Otherwise, the eye should be closed as much as possible. No rubbing of eyes after procedure.

Does cross-linking improve vision?
The cross linking procedure adds cross-links or “cross beams” to the cornea, making it more stable, holding its shape and focusing power better. These new cross-links help strengthen the cornea which stops the thinning process and further loss of vision.

in which conditions CXL can be used?

Keratoconus

Pellucid Marginal Degeneration

Ectasia following Refractive Surgery

Infective Keratitis – PACK CXL

Bullous Keratopathy

Number of CXL procedures performed at LJEI

Corneal Collagen Cross Linking Procedures

Why to choose LJ Eye Institute for Collagen Cross Linking Surgery?

At LJ Eye Institute we use most advanced Eye Transplant techniques whichever is available in the world, which further help to increase the success rate. Where using traditional techniques the success rate is 70% to 75%, the new techniques increase the success rate to 90% to 95%.These advanced techniques includes DMEK, DALK, DSEK, using such techniques we need not to change whole Cornea and we change only One or required number of layers of Cornea.

Technology @ LJEI

Technology Available For CXL at LJEI

LJ Eye Institute employs ultra-advanced technologies for Cornea Transplant procedures.

  • We utilize Femtosecond LASER technology for Cornea Transplants, ensuring precision and accuracy compared to conventional blade methods.
  • Our facility is equipped with specialized equipment including Specular Microscope for assessing corneal power, Topography, Pentacam, Anterion, and OCT for comprehensive evaluation.
  • We integrate the latest available technologies from around the world to achieve the highest success rates in Cornea Transplants.
  • For pediatric cases, we have a dedicated spare system and have extensively researched Pediatric Cornea diseases, with publications in national and international medical journals.
  • LJ Eye Institute is at the forefront of Stem Cell Transplantation, particularly in the pioneering SLET technique, with numerous published papers showcasing our advancements and modifications in the field.

Still Have Questions?

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BEST CORNEA HOSPITAL IN INDIA

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